What is the recommended puppy vaccination timeline?

Published: November 27, 2025
Updated: November 27, 2025

Did you know your pup's vaccination schedule protects them from parvo and distemper? Core vaccines are typically administered between 6-8 weeks, providing crucial protection during those early, vulnerable months. Keeping this schedule ensures they're vaccine-protected before the exposure risk rises. Scheduling exactly like this saves lives!

6-8 Weeks

  • First DHP/DHPP shot against distemper, hepatitis, parvovirus
  • Small breeds may start earlier than large breeds
  • Vet examines puppy health before administration

10-12 Weeks

  • Second DHP/DHPP booster plus leptospirosis vaccine
  • Non-core vaccines begin based on lifestyle risks
  • Monitor for mild reactions like tiredness

14-16 Weeks

  • Final DHP/DHPP booster and rabies vaccine
  • Leptospirosis booster for complete protection
  • Rabies documentation required by law
Vaccine Protection Timeline
AgeAfter first shotsImmunity Development
Partial protection begins
Safe Socialization
Private yards only
AgeAfter second shotsImmunity Development
Enhanced disease resistance
Safe Socialization
Controlled meetings
AgeAfter final boostersImmunity Development
Full protection established
Safe Socialization
All safe environments
Wait 7 days after final shots before dog parks

Your veterinarian customizes this schedule for breed size and local exposure risk. Toy breeds, for instance, often finish earlier than giant breeds. Puppies in urban areas may require leptospirosis shots earlier. In any case, always complete the series by 16 weeks for maximum protection.

Non-core vaccines - timing is similar, but they depend on the risk of exposure. Bordetella, for example, is typically administered at about 10 weeks if you are boarding your puppy. Lyme disease vaccines are recommended for individuals living in areas with a high tick population. Discuss these options with your puppy's veterinarian at their first visit.

Read the full article: Puppy Vaccination Timeline: Complete Guide

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