What vaccination schedule should puppies follow?

Published: November 26, 2025
Updated: November 26, 2025

Your puppy's vaccination schedule should be in lockstep with their development. Miss the boat on this one, and your pup is at risk for parvo and other deadly diseases. Core vaccines trail a phase-based timeline that begins while you are actively socializing your puppy. These vaccines provide them with an opportunity to explore their world safely.

Socialization Phase (6-8 weeks)

  • First DHPP vaccine against distemper and parvovirus
  • Initial protection during critical fear period
  • Avoid public spaces until seven days post-shot
  • Begin controlled socialization at home

Juvenile Phase (10-12 weeks)

  • Second DHPP booster strengthens immunity
  • Bordetella vaccine for kennel cough prevention
  • Leptospirosis vaccine in high-risk regions
  • Limit contact with unknown dogs still

Adolescence (14-16 weeks)

  • Final DHPP booster completes core protection
  • Rabies vaccination required by law
  • Lyme disease vaccine in tick-prone areas
  • Full park access seven days later
Breed Size Vaccination Variations
Breed SizeSmall (<20 lbs)First Shots6 weeksRabies Timing14 weeksSpecial Considerations
Higher parvo risk needs earlier start
Breed SizeLarge (50-90 lbs)First Shots7 weeksRabies Timing16 weeksSpecial Considerations
Longer intervals between boosters
Breed SizeGiant (>90 lbs)First Shots8 weeksRabies Timing18 weeksSpecial Considerations
Slower immune response delays protection
Always confirm timing with your veterinarian

The existence of regional disease risks affects vaccine selection. While parvovirus is more prevalent in urban areas, it is essential to start protecting against it early. Lyme disease may also be a consideration in wooded environments. Your veterinarian is aware of the threats unique to your area and develops schedules that are appropriate for your specific environment.

Booster Shots Keep You Protected Into Adulthood DHPP updates every year or so will inhibit the chance of an immunity gap. Required rabies boosters are administered every one to three years, as per local law. Keep records of your immunizations for someday these pieces of paper will prove vital when your pet is boarded, travels abroad, or has a "pet-sitter" look after him while you are away.

That vaccination schedule based on lifestyle is non-core. Bordetella protection is typically required for boarding facilities. Leptospirosis prevention would apply to hunting dogs. Show dogs often benefit from receiving rabies for canine influenza. Discuss classes of activities with your veterinarian for individual vaccine recommendations for your puppy.

Observe for uncommon allergic reactions, including facial swelling and lethargy. They typically resolve within hours at home. Severe allergic reactions occur immediately and require emergency services. Report any allergic reactions, whether mild or severe so that adjustments can be made for future immunizations. This is important to maintain safety.

Read the full article: Puppy Growth Stages: Complete Development Guide

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